Article
HFE H63D polymorphism as a modifier of the effect of cumulative lead exposure on pulse pressure: the Normative Aging Study.
Environmental health perspectives - 1 Sept 2010
Zhang Aimin, Park Sung Kyun, Wright Robert O, Weisskopf Marc G, Mukherjee Bhramar, Nie Huiling, Sparrow David, Hu Howard
Abstract excerpt
BACKGROUND: Cumulative lead exposure is associated with a widened pulse pressure (PP; the -difference between systolic and diastolic blood pressure), a marker of arterial stiffness and a predictor of cardiovascular disease. Polymorphisms in the hemochromatosis gene (HFE) have been shown to modify the impact of cumulative lead exposure on measures of adult cognition and cardiac function. OBJECTIVES: We examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.