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Article

Combined effects of glutathione S-transferase polymorphisms and thyroid cancer risk.

Cancer genetics and cytogenetics - 1 May 2004

Gaspar Jorge, Rodrigues Sónia, Gil Octávia Monteiro, Manita Isabel, Ferreira Teresa Cruz, Limbert Edward, Gonçalves Luzia, Pina Julieta Esperança, Rueff José

Abstract excerpt

Since exposure to ionizing radiation, a risk factor for thyroid cancer, may produce genotoxins potentially eliminated by glutathione-S-transferases, we conducted a case control study to evaluate the role of the GSTM1- and GSTT1-null genotypes and GSTP1 polymorphisms in thyroid cancer. The frequency of GSTP1 Ile/Ile, GSTM1-, and GSTT1-null genotypes was increased in cancer patients when compared with control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15120911
DOI: 10.1016/j.cancergencyto.2003.09.018

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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