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Article

Combined GSTM1 and GSTT1 null genotypes are associated with a lower risk of papillary thyroid cancer.

Journal of endocrinological investigation - 1 Jun 2008

Lemos M C, Coutinho E, Gomes L, Carrilho F, Rodrigues F, Regateiro F J, Carvalheiro M

Abstract excerpt

Individual susceptibility to cancer is influenced by polymorphisms of genes encoding drug-metabolizing enzymes such as the glutathione S-transferases (GST). The null polymorphisms of the GSTM1 and GSTT1 genes have been associated to a modified risk of several cancers but studies of thyroid cancer have produced conflicting results. The aim of this study was to investigate the relationship between these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18591888
DOI: 10.1007/BF03346405

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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