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Article

The null genotype of glutathione s-transferase M1 and T1 locus increases the risk for thyroid cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2002

Morari Elaine Cristina, Leite Janaína Luísa Pereira, Granja Fabiana, da Assumpção Lígia Vera Montalli, Ward Laura Sterian

Abstract excerpt

Susceptibility to chemical carcinogens plays an important role in the development of most cancers. Several polymorphisms of human drug-metabolizing enzymes influence this individual susceptibility. The genes that encode the isoenzymes of the glutathione s-transferase (GST) system present a polymo...

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Source

Identifiers

PMID: 12433731

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12433731-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The null genotype of glutathione s-transferase M1 and T1 locus increases the risk for thyroid cancer.PMID 12433731Read ↗

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Comparative analysis of the prevalence of the glutathione S-transferase (GST) system in malignant and benign thyroid tumor cells.Semantic proximity Read ↗

Association of the glutathione s-transferase m1, t1 polymorphisms with cancer: evidence from a meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase T1 null polymorphism and the risk for head and neck cancer.Semantic proximity Read ↗

Genetic deletions of GSTM1 and GSTT1 in head and neck cancer: review of the literature from 2000 to 2012.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms and risk of differentiated thyroid carcinomas: a case-control analysis.Semantic proximity Read ↗

GST profiling may be useful in the screening for thyroid nodule malignancy.Semantic proximity Read ↗

GSTM1 null polymorphism prevalence in tobacco users, oral leukoplakia and oral squamous cell carcinoma patients in South Indian population: A polymerase chain reaction study.Semantic proximity Read ↗

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