Article
[Transferase S-glutathione class pi gene (GSTP1) polymorphism in thyroid cancer patients].
Endokrynologia Polska - 1 Jan 2000
Marciniak Paweł, Drobnik Katarzyna, Ziemnicka Katarzyna, Gut Paweł, Słomski Ryszard, Sowiński Jerzy
Abstract excerpt
INTRODUCTION: One of the potential genes which can increase the risk of cancer is GSTP1 gene. It encodes enzyme called glutathione S-transferase pi class, which is involved in the detoxification of a variety of potential carcinogenic compounds. Polymorphism in this gene can cause the amino acid substitution. This substitution, close to the substrate binding site, changes the enzymatic activity for particular...
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