Article
GST profiling may be useful in the screening for thyroid nodule malignancy.
Cancer letters - 25 Jun 2004
Granja Fabiana, Morari Joseane, Morari Elaine C, Correa Luiz A C, Assumpção Lígia V M, Ward Laura S
Abstract excerpt
Screening tools are of utmost necessity in order to identify individuals at risk for thyroid nodule cancer. The polymorphic inheritance of human drug-metabolizing enzymes, such as those encoded by the Glutathione-S-Transferase (GST) system, plays an important role in the development of most human cancers. GSTP1 enzyme is the most important detoxification enzyme in human head and neck tissues. An aminoacid...
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