Article
A sequencing-based typing method for HLA-DQA1 alleles.
Human immunology - 1 Apr 2004
Rajalingam Raja, Ge Ping, Reed Elaine F
Abstract excerpt
Sequencing-based typing (SBT) is the most comprehensive method for characterizing human leukocyte antigen gene polymorphisms. Development of a SBT method for DQA1 is hampered because of a deletion of codon 56 in nearly half of the known DQA1 alleles. Sequence electropherograms of heterozygous samples comprising a deletion allele and a non-deletion allele display misalignment after codon 56 because of a three...
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