Article
Resolution of HLA class I sequence-based typing ambiguities by group-specific sequencing primers.
Tissue antigens - 1 Mar 2011
Lebedeva T V, Mastromarino S A, Lee E, Ohashi M, Alosco S M, Yu N
Abstract excerpt
The increasing demand for allele-level human leukocyte antigen (HLA) typing has led the sequence-based typing (SBT) to become the preferred method. In turn, the steady increase in the number of HLA alleles driven by the adoption of SBT as the ultimate typing method leads to the ever increasing number of cis/trans ambiguities. Over the last few years, additional sequencing with the commercially available...
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