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Article

Omeprazole treatment: genotoxicity biomarkers, and potential to induce CYP1A2 activity in humans.

Human & experimental toxicology - 1 Mar 2004

Sinués Blanca, Fanlo Ana, Bernal Maria Luisa, Val Marta, Mayayo Esteban

Abstract excerpt

Omeprazole is one of the most used acid-suppressing medications. This fact emphasizes the questions concerning the safety of this compound. Healthy volunteers (n=33) were included in this prospective study. All study subjects were analysed for their CYP2C19 genotype. Of the 33 individuals, 24 were homozygous for the wild type CYP2C19*1 allele, 7 were heterozygous for the CYP2C19*2 variant allele, and 2 were...

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PMID: 15119530
DOI: 10.1191/0960327104ht431oa

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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