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Pharmacological Effects and Toxicogenetic Impacts of Omeprazole: Genomic Instability and Cancer

29 Mar 2020

Abstract excerpt

Omeprazole (OME) is commonly used to treat gastrointestinal disorders. However, long-term use of OME can increase the risk of gastric cancer. We aimed to characterize the pharmacological effects of OME and to correlate its adverse effects and toxicogenetic risks to the genomic instability mechanisms and cancer-based on database reports. Thus, a search (till Aug 2019) was made in the PubMed, Scopus, and...

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PMID: 32308801
DOI: 10.1155/2020/3457890

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