Article
Characterization of the molecular mechanisms of quinolone resistance in Yersinia enterocolitica O:3 clinical isolates.
The Journal of antimicrobial chemotherapy - 1 Jun 2004
Capilla S, Ruiz J, Goñi P, Castillo J, Rubio M C, Jiménez de Anta M T, Gómez-Lus R, Vila J
Abstract excerpt
OBJECTIVES: The aim of this study was to determine the roles of mutations in the gyrA and parC genes and the overexpression of efflux pump(s) as mechanisms of resistance to quinolones. Forty-five Yersinia enterocolitica O:3 clinical isolates (41 nalidixic acid-resistant, three nalidixic acid-susceptible and one nalidixic acid-resistant strain obtained in vitro) were analysed. RESULTS: All the nalidixic...
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