[Resistance to quinolones and beta-lactams in Salmonella enterica due to mutations in topoisomerase-encoding genes, altered cell permeability and expression of an active efflux system].

doi:10.1016/s0213-005x(04)73067-0

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Article

[Resistance to quinolones and beta-lactams in Salmonella enterica due to mutations in topoisomerase-encoding genes, altered cell permeability and expression of an active efflux system].

Enfermedades infecciosas y microbiologia clinica - 1 Apr 2004

Miró Elisenda, Vergés Clara, García Isabel, Mirelis Beatriz, Navarro Ferrán, Coll Pere, Prats Guillermo, Martínez-Martínez Luis

Abstract excerpt

BACKGROUND: The mechanisms of resistance to fluoroquinolones and beta-lactams were studied in isolates of Salmonella enterica resistant to both antimicrobial groups, isolated over time from two patients treated with fluoroquinolones. METHODS: The clonal relationships among the various strains was established by serotyping and pulsed-field gel electrophoresis. MICs for beta-lactams, quinolones, chloramphenicol and...

Topics

Adult
Aged
Amino Acid Substitution
Anti-Infective Agents
Bacterial Outer Membrane Proteins
Bacterial Proteins
Biological Transport, Active
Cell Membrane Permeability
DNA Gyrase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA Mutational Analysis

DNA Topoisomerase IV

DNA, Bacterial

Dipeptides

Drug Resistance, Multiple, Bacterial

Gastroenteritis

Humans

Male

Microbial Sensitivity Tests

Source

Open in PubMed

Identifiers

PMID: 15056435
DOI: 10.1016/s0213-005x(04)73067-0

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