Article
Fluoroquinolone and multidrug resistance phenotypes associated with the overexpression of AcrAB and an orthologue of MarA in Yersinia enterocolitica.
International journal of medical microbiology : IJMM - 1 Nov 2010
Fàbrega Anna, Roca Ignasi, Vila Jordi
Abstract excerpt
Quinolone resistance among clinical isolates is of increasing importance. This phenotype particularly affects the nalidixic acid resistance levels and is also increasing among Yersinia enterocolitica strains. This study investigated the quinolone resistance mechanisms acquired in vitro by a Y. enterocolitica clinical isolate exposed to increasing concentrations of ciprofloxacin in a multi-step selection process....
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- DNA, Bacterial
- Drug Resistance, Multiple, Bacterial
- Fluoroquinolones
- Gene Expression
- Gene Expression Profiling
- Humans
- Membrane Transport Proteins
- Microbial Sensitivity Tests