Article
Phenotypic and genotypic quinolone resistance in Escherichia coli underlining GyrA83/87 mutations as a target to detect ciprofloxacin resistance.
The Journal of antimicrobial chemotherapy - 1 Sept 2020
Muggeo Anaëlle, Cambau Emmanuelle, Amara Marlène, Micaëlo Maïté, Pangon Béatrice, Bajolet Odile, Benmansour Hanaa, de Champs Christophe, Guillard Thomas
Abstract excerpt
BACKGROUND: Quinolone resistance (QR) is one component of the MDR emerging in Escherichia coli and is of particular concern given the widespread use of fluoroquinolones. OBJECTIVES: To characterize the QR phenotypes and genotypes in E. coli responsible for bloodstream infections and to propose molecular determinants that could be targeted to predict ciprofloxacin resistance. METHODS: E. coli isolates from blood...
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