Article
The neurofibromatosis type 2 gene product, schwannomin, suppresses growth of NIH 3T3 cells.
Cancer research - 1 Jun 1995
Lutchman M, Rouleau G A
Abstract excerpt
Cancer is a multistep process that involves the activation of oncogenes and the inactivation of antioncogenes. Recently, a new putative tumor suppressor, the neurofibromatosis type 2 (NF2) gene, was mapped to chromosome 22, cloned, and found to encode for a new protein, merlin/schwannomin, a memb...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Cell Division
- DNA, Neoplasm
- Epidermal Growth Factor
- Genes, Neurofibromatosis 2
- Humans
- Membrane Proteins
- Mice
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins