Article
Methyl-CpG-binding domain 2: a protective role in bladder carcinoma.
Cancer - 1 May 2004
Zhu Yong, Spitz Margaret R, Zhang Hui, Grossman H Barton, Frazier Marsha L, Wu Xifeng
Abstract excerpt
BACKGROUND: MBD2, a methyl-CpG-binding domain 2 protein, has attracted much attention because of its role in epigenetic regulation of gene expression. In addition to transcriptional repression, MBD2 has also been shown to catalyze demethylation by directly removing methyl groups from 5-methylcyto...
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