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Article

Methyl-CpG binding domain 1 gene polymorphisms and risk of primary lung cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2005

Jang Jin-Sung, Lee Su Jeong, Choi Jin Eun, Cha Sung Ick, Lee Eung Bae, Park Tae In, Kim Chang Ho, Lee Won Kee, Kam Sin, Choi Je-Yong, Kang Young Mo, Park Rang-Woon, Kim In-San, Cho Young Lae, Jung Tae Hoon, Han Sung Beom, Park Jae Yong

Abstract excerpt

The methyl-CpG binding domain 1 (MBD1) protein plays an important role for transcriptional regulation of gene expression. Polymorphisms and haplotypes of the MBD1 gene may have an influence on MBD1 activity on gene expression profiles, thereby modulating an individual's susceptibility to lung cancer. To test this hypothesis, we investigated the association of MBD1 -634G>A, -501delT (-501 T/T, T/-, -/-), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16284366
DOI: 10.1158/1055-9965.EPI-05-0423

Genes

MBD1

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