Article
Genetic epidemiology of the beta s gene.
Bailliere's clinical haematology - 1 Apr 1992
Nagel R L, Fleming A F
Abstract excerpt
The beta s gene arose at least four times in Africa, with three of these mutations expanding through diverse ethnic groups, but limited to definite geographical areas: Atlantic west Africa for the Senegal haplotype linked beta s; central west Africa for the Benin haplotype; and equatorial, eastern and southern Africa for the Bantu haplotype. The fourth mutation (linked to the Cameroon haplotype) is restricted to...
Topics
- Africa
- Anemia, Sickle Cell
- Base Sequence
- Gene Frequency
- Globins
- Hemoglobin, Sickle
- Humans
- India
- Malaria
- Molecular Sequence Data
- Mutation
- Saudi Arabia