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Article

Genetic epidemiology of the beta s gene.

Bailliere's clinical haematology - 1 Apr 1992

Nagel R L, Fleming A F

Abstract excerpt

The beta s gene arose at least four times in Africa, with three of these mutations expanding through diverse ethnic groups, but limited to definite geographical areas: Atlantic west Africa for the Senegal haplotype linked beta s; central west Africa for the Benin haplotype; and equatorial, eastern and southern Africa for the Bantu haplotype. The fourth mutation (linked to the Cameroon haplotype) is restricted to...

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PMID: 1511179
DOI: 10.1016/s0950-3536(11)80023-5

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