Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence and Diversity of Haplotypes of Sickle Cell Disease in the Eastern Province of Saudi Arabia.

Hemoglobin - 1 Mar 2020

Al-Ali Amein K, Alsulaiman Ahmed, Alzahrani Alhusain J, Obeid Obeid T, Vatte Chitti Babu, Cyrus Cyril, Alnafie Awatif N, Alali Rudaynah A, Alfarhan Mohammed, Mozeleski Brian, Steinberg Martin H

Abstract excerpt

Hb F modulates sickle cell disease. Five major haplotypes of the β-globin gene cluster are associated with sickle cell disease. In the Eastern Province of Saudi Arabia, the Arab-Indian (AI) is most common. Single nucleotide polymorphism (SNP) genotyping (rs3834466, rs28440105, rs10128556, and rs968857) was carried out by nuclease allelic discrimination assay with target-specific forward and reverse primers,...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Anemia, Sickle Cell
Share to beta-Globins
Share to Child, Preschool
Share to Haplotypes
Share to Hemoglobin, Sickle
Share to Prevalence
Share to Saudi Arabia

Source

Identifiers

PMID: 32448003
DOI: 10.1080/03630269.2020.1739068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence and Diversity of Haplotypes of Sickle Cell Disease in the Eastern Province of Saudi Arabia.PMID 32448003Read ↗

ß-Globin gene cluster haplotypes in Moroccan sickle cell disease patients: diversity pilot study.Semantic proximity Read ↗

Sickle cell disease in Middle East Arab countriesSemantic proximity Read ↗

Hb F Levels in Indian Sickle Cell Patients and Association with the HBB Locus Variant rs10128556 (C>T), and the HBG XmnI (Arab-Indian) Variant.Semantic proximity Read ↗

Genetic patterns & public health implications of sickle cell anaemia across populations: A systematic review.Semantic proximity Read ↗

Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemiaSemantic proximity Read ↗

Genotypic Diversity among Angolan Children with Sickle Cell Anemia.Semantic proximity Read ↗

β‐Globin gene cluster haplotypes in sickle cell patients from southwest IranSemantic proximity Read ↗

Prevalence and Regional Distribution of Beta-Hemoglobin Variants in Saudi Arabia: Insights from the National Premarital Screening Program" Running Title: Burden of Beta-Globin Variants in Saudi ArabiaSemantic proximity Read ↗

Epidemiology of sickle cell disease in Saudi Arabia.Semantic proximity Read ↗

Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans.Semantic proximity Read ↗

Sickle cell anemia: clinical diversity and beta S-globin haplotypesSemantic proximity Read ↗

Unusual β-Globin Haplotype Distribution in Newborns from Bengo, AngolaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.