Article
Sickle cell anemia and beta-gene cluster haplotypes in Cuba.
American journal of hematology - 1 Jun 1995
Muniz A, Corral L, Alaez C, Svarch E, Espinosa E, Carbonell N, di Leo R, Felicetti L, Nagel R L, Martinez G
Abstract excerpt
We have studied 91 patients with SS genotype, 44 children and 47 adults. Excluding the Cameroon and atypical haplotypes, the distribution in the children's sample exhibited 43% Benin, 38% Bantu, and 3% Senegal. In adults, the sample exhibited 46% Benin, 30% Bantu, and 9% Senegal (chi 2: 13.511, 2 df, P = 0.001). When the whole sample of 198 chromosomes (SS, SC, and S/beta thal) is considered, we find that the...
Topics
- Adolescent
- Adult
- Africa
- Anemia, Sickle Cell
- Child
- Child, Preschool
- Chromosomes
- Cuba
- Genotype
- Haploidy
- Hemoglobinopathies
- Humans
