Article
Molecular epidemiology of the thalassaemias (including haemoglobin E).
Bailliere's clinical haematology - 1 Jan 1992
Hill A V
Abstract excerpt
The thalassaemias are the most common genetic disorders of man, and over the last decade the molecular epidemiology of these defects has been studied in detail. After briefly reviewing the great diversity of mutations giving rise to these conditions, four global regions are discussed in more detail. The thalassaemias, of which haemoglobin E is one, are most frequent in Asia, where recent work has defined the...
Topics
- Adult
- Africa
- Asia
- Case-Control Studies
- Child
- Chromosome Deletion
- Cluster Analysis
- Europe
- Female
- Fetal Diseases
- Gene Frequency
- Genes
- Genotype