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Article

ß-Globin gene cluster haplotypes in Moroccan sickle cell disease patients: diversity pilot study.

African health sciences - 1 Jun 2026

Ismaili Fatima Zahra Alaoui, Derkaoui Touria, Hamjane Nadia, Barakat Amina, Nourouti Naima Ghailani, Mechita Mohcine Bennani

Abstract excerpt

Background: Sickle cell disease (SCD) is the most common inherited blood disorder worldwide. Although monogenic, it presents substantial clinical heterogeneity influenced by genetic modifiers, including haplotypes and fetal hemoglobin (HbF) levels. Objectives: This pilot cross-sectional study aimed to characterize, for the first time, the βS gene haplotype distribution among Moroccan patients with sickle cell...

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Identifiers

PMID: 42564674
DOI: 10.4314/ahs.v26i2.7
PMCID: PMC13444292

Genes

SCD

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