Article
Identification of β-globin haplotypes linked to sickle hemoglobin (Hb S) alleles in Mazandaran province, Iran.
Genes & genetic systems - 13 May 2017
Aghajani Faeghe, Mahdavi Mohammad Reza, Kosaryan Mehrnoush, Mahdavi Mehrad, Hamidi Mohaddase, Jalali Hossein
Abstract excerpt
Carrier frequency of the βS allele has been reported to be 0.19% in Mazandaran province, northern Iran. Haplotype analysis of the βS allele helps trace the origin of its encoded hemoglobin (Hb) variant, Hb S, in a region. The aim of this study was to investigate the haplotypes associated with βS alleles in Mazandaran province. Capillary electrophoresis was carried out to detect individuals suspected to have a βS...
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