Article
Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos.
Molecular biology of the cell - 1 Apr 2004
Park Eui Kyun, Warner Neil, Bong Yong-Sik, Stapleton David, Maeda Ryu, Pawson Tony, Daar Ira O
Abstract excerpt
The Eph family of receptor tyrosine kinases regulates numerous biological processes. To examine the biochemical and developmental contributions of specific structural motifs within Eph receptors, wild-type or mutant forms of the EphA4 receptor were ectopically expressed in developing Xenopus embryos. Wild-type EphA4 and a mutant lacking both the SAM domain and PDZ binding motif were constitutively tyrosine...
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