Article
Vitamin D receptor polymorphisms are associated with Graves' disease in German and Polish but not in Serbian patients.
Thyroid : official journal of the American Thyroid Association - 1 Oct 2005
Ramos-Lopez Elizabeth, Kurylowicz Alina, Bednarczuk Tomasz, Paunkovic Jane, Seidl Christian, Badenhoop Klaus
Abstract excerpt
Diverse genes are candidates for susceptibility to Graves' disease, including the vitamin D receptor (VDR), which regulates the transcription of target genes in response to the active metabolite 1,25(OH)(2)D(3). We analyzed four polymorphisms of the VDR gene (ApaI, TaqI, BsmI, and FokI) in patients with Graves' disease (n = 789) and healthy controls (n = 823) from three European populations (German, Polish, and...
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