Article
Association between vitamin-D receptor gene FokI polymorphism and Graves' disease among Taiwanese Chinese.
Journal of clinical laboratory analysis - 1 Jan 2007
Chen Rong-Hsing, Chang Chwen-Tzuei, Chen Huey-Yi, Chen Wen-Chi, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
1,25(OH)(2)D(3), exerting its biological effects through the vitamin-D receptor (VDR), plays a role in the modulation of the human immune system. The aim of this study was to test for the presence of an association between VDR gene polymorphism and the susceptibility to Graves' disease (GD) for Taiwanese Chinese. Using a polymerase chain reaction (PCR)-based restriction analysis, we screened the VDR exon 2 start...
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