Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental Study

16 Oct 2016

Abstract excerpt

BACKGROUND Endometriosis can cause dysmenorrhea and infertility. Its pathogenesis has not yet been clarified and its treatment continues to pose enormous challenges. The protein tyrosine phosphatase (PTEN) gene is a tumor suppressor gene. The aim of this study was to investigate the role and significance of PTEN protein in the occurrence, development, and treatment of endometriosis through changes in apoptosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Endometriosis Research and Treatment
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27744455
DOI: 10.12659/msm.901091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vitro and In Vivo Effects of Tumor Suppressor Gene PTEN on Endometriosis: An Experimental StudyPMID 27744455Read ↗

Role of endometriosis in cancer and tumor development.Semantic proximity Read ↗

PTEN and Gynecological CancersSemantic proximity Read ↗

Downregulation of Circ_0000673 Promotes Cell Proliferation and Migration in Endometriosis Via Suppressing PTENSemantic proximity Read ↗

Prognostic Analysis of PTEN Mutation in Endometrial CarcinomaSemantic proximity Read ↗

Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosisSemantic proximity Read ↗

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.Semantic proximity Read ↗

A Systematic Review and Bioinformatics Study on Genes and micro-RNAs Involving the Transformation of Endometriosis into Ovarian CancerSemantic proximity Read ↗

The regulation of PTEN: Novel insights into functions as cancer biomarkers and therapeutic targetsSemantic proximity Read ↗

PTEN mutation: A potential prognostic factor associated with immune infiltration in endometrial carcinoma.Semantic proximity Read ↗

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivoSemantic proximity Read ↗

Decoding PTEN: from biological functions to signaling pathways in tumors.Semantic proximity Read ↗

Reversal of the malignant phenotype of ovarian cancer A2780 cells through transfection with wild-type PTEN gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.