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Article

[Research on the mechanisms of PTEN gene inactivation in ovarian cancer].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 May 2005

Lü Qing-jie, Zhao Xiao-dong, Song Ji-ye, Li Xiao-han, Ma Ying, Meng Hui, Jiang Wei-guo

Abstract excerpt

OBJECTIVE: To investigate the mechanisms of PTEN gene inactivation starting from DNA, mRNA and protein levels in ovarian cancers. METHODS: Tumor tissue samples were obtained from 48 patients with epithelial ovarian cancers. Using four polymorphic markers (D10s541, D10s583, D10s1687 and D10s2491)...

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Topics

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Share to Chromosomes, Human, Pair 10
Share to Gene Deletion
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 16181546

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16181546-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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