Article
Role of exon 7 PTEN Gene in Endometrial Carcinoma.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Kafshdooz Leila, Kafshdooz Taiebeh, Tabrizi Ali Dastranj, Mohaddes Ardabili Seyyed Mojtaba, Akbarzadeh Abolfazl, Gharesouran Jalal, Ghojazadeh Morteza, Farajnia Safar
Abstract excerpt
BACKGROUND: Endometrial carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in Iranian women after breast, colorectal and lung cancers. Various genetic alterations appear to be early events in the pathogenesis of endometrial carcinoma and it seems that PTEN is the most commonly mutated gene in the endometrioid subtype. The aim of the present study was to...
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