Article
[Study of the mutation and expression of PTEN gene in endometrial carcinoma and epithelial ovarian cancer].
Zhonghua fu chan ke za zhi - 1 Oct 2002
Che Yanci, Yao Qin, Dai Shuzhen, Luo Bing, Wang Yankui
Abstract excerpt
OBJECTIVE: To study the relationship between the mutation and protein expression of PTEN and carcinogenesis of endometrial carcinoma and epithelial ovarian cancer. METHODS: The mutations of Exon5, 8 of PTEN in epithelial ovarian cancer tissues and endometrial carcinoma tissues were examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and DNA sequence analysis; and...
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