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Article

Discrimination of single amino acid mutations of the p53 protein by means of deterministic singularities of recurrence quantification analysis.

Proteins - 15 May 2004

Porrello Alessandro, Soddu Silvia, Zbilut Joseph P, Crescenzi Marco, Giuliani Alessandro

Abstract excerpt

p53 is mutated in roughly 50% of all human tumors, predominantly in the DNA-binding domain codons. Structural, biochemical, and functional studies have reported that the different p53 mutants possess a broad range of behaviors that include the elimination of the tumor-suppression function of wild-type protein, the acquisition of dominant-negative function over the wild-type form, and the establishment of...

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PMID: 15103636
DOI: 10.1002/prot.20075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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