Frailness and resilience of gene networks predicted by detection of co-occurring mutations via a stochastic perturbative approach.

Abstract excerpt

In recent years complex networks have been identified as powerful mathematical frameworks for the adequate modeling of many applied problems in disparate research fields. Assuming a Master Equation (ME) modeling the exchange of information within the network, we set up a perturbative approach in order to investigate how node alterations impact on the network information flow. The main assumption of the perturbed...

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