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Article

Osteoclast-like cell formation by circulating myeloma B lymphocytes: role of RANK-L.

Leukemia & lymphoma - 1 Feb 2004

Calvani Nicola, Silvestris Franco, Cafforio Paola, Dammacco Franco

Abstract excerpt

Excessive bone resorption in multiple myeloma (MM), a malignancy of B lymphoid origin, is mediated through osteoclasts, which respond to local osteoclast-activating factors produced by tumor cells within the bone marrow microenvironment. Direct bone resorption by myeloma cells is investigated in the present study, since a connection between B lymphocytes and osteoclast differentiation pathways has been recently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15101727
DOI: 10.1080/10428190310001595696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Osteoclast-like cell formation by circulating myeloma B lymphocytes: role of RANK-L.PMID 15101727Read ↗

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