Article
A novel mature B-cell line (DOBIL-6) producing both parathyroid hormone-related protein and interleukin-6 from a myeloma patient presenting with hypercalcaemia.
British journal of haematology - 1 Jun 1998
Ohmori M, Nagai M, Fujita M, Dobashi H, Tasaka T, Yamaoka G, Kawanishi K, Taniwaki M, Takahara J
Abstract excerpt
A novel human EBV-negative B-cell line, designated DOBIL-6, was established from a patient with non-secretary myeloma. The DOBIL-6 cell has cytoplasmic gamma protein and expresses CD19, 20, 38, 45RO, VLA-4 and PCA-1 antigens, but lacks CD10, 45RA and VLA5 antigens. Chromosome analysis showed that...
Topics
- Aged
- B-Lymphocytes
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 14
- Fatal Outcome
- Female
- Humans
- Hypercalcemia
- Interleukin-6
- Karyotyping
- Multiple Myeloma
- Parathyroid Hormone-Related Protein
- Phenotype
- Polymerase Chain Reaction