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Article

Upregulation of osteoblast apoptosis by malignant plasma cells: a role in myeloma bone disease.

British journal of haematology - 1 Jul 2003

Silvestris Franco, Cafforio Paola, Tucci Marco, Grinello Daniela, Dammacco Franco

Abstract excerpt

Typical features of multiple myeloma (MM) are osteolytic lesions and severely affected bone regeneration. This study of 53 MM patients demonstrates an enhancement of osteoblast cytotoxicity by malignant myeloma cells via the upregulation of apoptogenic receptors, including Fas ligand (Fas-L) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12823344
DOI: 10.1046/j.1365-2141.2003.04374.x

Genes

MCC
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12823344-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Upregulation of osteoblast apoptosis by malignant plasma cells: a role in myeloma bone disease.PMID 12823344Read ↗

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