Article
Improved production of spiramycin by mutant Streptomyces ambofaciens.
Journal of Zhejiang University. Science - 1 Jun 2004
Jin Zhi-hua, Cen Pei-lin
Abstract excerpt
Strain improvement and medium optimization to increase the productivity of spiramycin were carried out. Of oil tolerant mutant strains screened, one mutant, Streptomyces ambofaciens XC 2-37, produced 9% more spiramycin than the parent strain S. ambofaciens XC 1-29. The effects of soybean oil and propyl alcohol on spiramycin production with S. ambofaciens XC 2-37 were studied. The potency of S. ambofaciens XC 2-37...
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