Article
Improvement of industry-applied rifamycin B-producing strain, Amycolatopsis mediterranei, by rational screening.
The Journal of general and applied microbiology - 1 Dec 2002
Jin Zhi Hua, Lin Jiang Ping, Xu Zhi Nan, Cen Pei Lin
Abstract excerpt
An industrially applied rifamycin B-producing strain, Amycolatopsis mediterranei XC 1-02, was used for further screening. A special mutation and screening procedure was adopted to select a strain, which can alleviate the inhibition caused by both aromatic amino acid and p-hydroxybenzoic acid in the pathway of rifamycin B biosynthesis as well as enhance the production of propionate, one of the precursors of...
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