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Article

Enhanced production of a novel cytotoxic chromone oxalicumone A by marine-derived mutant Penicillium oxalicum SCSIO 24-2.

Applied microbiology and biotechnology - 1 Nov 2013

Zhang Xiao-Yong, Bao Jie, Zhong Juan, Xu Xin-Ya, Nong Xu-Hua, Qi Shu-Hua

Abstract excerpt

Many marine natural products hold great potential for the development of new and much needed drugs. However, the production of active metabolites by marine-derived microorganisms is usually very low, and large-scale culture has to be involved to meet the need of chemical structural modification and deep pharmacy study. In order to enhance the production of a novel cytotoxic sulfur-containing chromone oxalicumone...

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PMID: 24061416
DOI: 10.1007/s00253-013-5203-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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