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Article

Optimization of the production medium for biosynthesis of antifungal antibiotic AK-111-81 by phosphate-deregulated mutant of Streptomyces hygroscopicus.

Applied biochemistry and biotechnology - 1 Jul 2009

Gesheva Victoria

Abstract excerpt

Experimental mathematical designs were applied for optimization of a nutrient medium for biosynthesis of the antifungal antibiotic AK-111-81 by phosphate-deregulated mutant of Streptomyces hygroscopicus 111-81. Antifungal antibiotic AK-111-81 possesses well-expressed activity against Fusarium graminearum and other phytopathogenic fungi. The level of the production of the antibiotic AK-111-81 on this medium is...

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PMID: 19529894
DOI: 10.1007/s12010-009-8629-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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