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Article

A Phenotypically Distinct Human Th2 Cell Subpopulation Is Associated With Development of Allergic Disorders in Infancy.

Allergy - 1 Apr 2025

Pizzarello Catherine R, Jackson Courtney M, Herman Katherine, Seppo Antti E, Rebhahn Jonathan, Scherzi Tyler, Berin M Cecilia, Looney R John, Mosmann Tim R, Järvinen Kirsi M

Abstract excerpt

BACKGROUND: Little is known about the ontogeny of T cell immunity during infancy in farming and urban lifestyles due to the lack of immunophenotyping in such birth cohorts. METHODS: Two birth cohorts (farming and urban) at differing risks and rates of allergic diseases were compared. Blood mononuclear cells were collected from infants at birth, and 6 and 12 months of age. Full spectrum flow cytometry, followed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39899007
DOI: 10.1111/all.16489
PMCID: PMC11971024

Genes

CCR4
CISH
FOXP3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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