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Article

The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2004

Kan-Mitchell June, Bisikirska Brygida, Wong-Staal Flossie, Schaubert Keri L, Bajcz Melissa, Bereta Michal

Abstract excerpt

The CTL response to the HLA-A*0201-restricted, HIV-1 p17 Gag(77-85) epitope (SLYNTVATL; SL9) has been extensively studied in patients. Although this reactivity is exceptionally prominent in chronically infected patients and inversely correlated to viral load, SL9-specific CTLs (SL9-CTLs) are rarely detected in acute infection. To explore the cellular basis for this unusual manifestation, SL9-CTLs primed ex vivo...

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Share to Cytotoxicity Tests, Immunologic
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

Share to Genes, T-Cell Receptor beta

Share to HIV Antigens

Share to HLA-A2 Antigen

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Source

Identifiers

PMID: 15100263
DOI: 10.4049/jimmunol.172.9.5249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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