Article
Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2011
van Bockel David J, Price David A, Munier Mee Ling, Venturi Vanessa, Asher Tedi E, Ladell Kristin, Greenaway Hui Yee, Zaunders John, Douek Daniel C, Cooper David A, Davenport Miles P, Kelleher Anthony D
Abstract excerpt
CD8(+) T cells play a significant role in the control of HIV replication, yet the associated qualitative and quantitative factors that determine the outcome of infection remain obscure. In this study, we examined Ag-specific CD8(+) TCR repertoires longitudinally in a cohort of HLA-B*2705(+) long-...
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