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Article

The role of interleukin-1 in seizures and epilepsy: a critical review.

Experimental neurology - 1 Apr 2009

Rijkers K, Majoie H J, Hoogland G, Kenis G, De Baets M, Vles J S

Abstract excerpt

Interleukin-1 (IL-1) has a multitude of functions in the central nervous system. Some of them involve mechanisms that are related to epileptogenesis. The role of IL-1 in seizures and epilepsy has been investigated in both patients and animal models. This review aims to synthesize, based on the currently available literature, the consensus role of IL-1 in epilepsy. Three lines of evidence suggest a role for IL-1:...

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Identifiers

PMID: 19162013
DOI: 10.1016/j.expneurol.2008.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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