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Article

Inflammation modifies breathing phenotype in mice with epilepsy.

Journal of neuroinflammation - 7 Jan 2026

Bhandare Amol Mohan, Boaten Adwoa, Dunkwu Dylan, Hill Jade, Balazs Biborka, Dale Nicholas

Abstract excerpt

Impaired CO₂ responsiveness in epilepsy can result in hypoventilation and hypercapnia and these respiratory disturbances are key contributors to Sudden Unexpected Death in Epilepsy (SUDEP). While mild to moderate inflammation is known to modulate respiratory function, its specific role in regulating respiratory responses in the context of epilepsy remains unclear. We studied the effects of lipopolysaccharide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41501814
DOI: 10.1186/s12974-025-03670-6
PMCID: PMC12870216

Genes

TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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