Article
Myosin-binding protein C (MyBP-C) in cardiac muscle and contractility.
Advances in experimental medicine and biology - 1 Jan 2003
Winegrad Saul
Abstract excerpt
Both the MyBP-C motif between C1 and C2 and the C5 module are important regions for implementing the effect of MyBP-C on myosin and on contractility but in different ways. C5 may determine the folding of MyBP-C and the manner in which MyBP-C interacts with myosin. In spite of its apparent importance this interaction does not appear to be physiologically regulated. Its alteration by mutation however can have a...
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