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Article

Polymorphisms of IL-1 beta gene in Japanese patients with Sjögren's syndrome and systemic lupus erythematosus.

The Journal of rheumatology - 1 Apr 2004

Muraki Yoshifumi, Tsutsumi Akito, Takahashi Reiko, Suzuki Eiji, Hayashi Taichi, Chino Yusuke, Goto Daisuke, Matsumoto Isao, Murata Hideyuki, Noguchi Emiko, Sumida Takayuki

Abstract excerpt

OBJECTIVE: Interleukin (IL)-1 beta is a proinflammatory cytokine involved in various immune responses. Five polymorphisms in the IL-1 beta gene have been described, and relationships between these polymorphisms and some autoimmune diseases have been reported. Evidence suggests that IL-1 beta may be involved in the destruction of salivary and lacrimal glands in Sjögren's syndrome (SS). We evaluated the...

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PMID: 15088297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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