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Article

The relationship between Interleukin 1 beta single nucleotide polymorphisms and systemic lupus erythematosus among the Chinese Han population.

Molecular immunology - 1 Sept 2025

Liu Mao, Ling Xiru, Tang Zhenboyang, Huang Chunyan, Wang Ping, Wu Jiqiang, He Yue, Chen Jie

Abstract excerpt

OBJECTIVE: Systemic lupus erythematosus (SLE) is a typical autoimmune disease whose etiology is related to genetic factors. This study is designed to evaluate the association between Single Nucleotide Polymorphisms (SNPs) of the Interleukin 1 beta (IL-1β) gene (rs16944, rs1143627, rs1143634) and SLE susceptibility and clinical characteristics in the Chinese Han population. METHODS: This case-control study...

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PMID: 40680524
DOI: 10.1016/j.molimm.2025.07.003

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