Article
Interleukin-1beta polymorphisms in Colombian patients with autoimmune rheumatic diseases.
Genes and immunity - 1 Dec 2004
Camargo J F, Correa P A, Castiblanco J, Anaya J-M
Abstract excerpt
Interleukin-1 beta (IL-1beta) exerts a range of inflammatory and immunomodulatory activities that are important in host defense and autoimmune response. The IL-1beta gene, located on chromosome 2 (2q13), is polymorphic. The influence of its polymorphism on 355 patients with autoimmune rheumatic diseases was examined. To this effect, 172 patients with rheumatoid arthritis (RA), 114 with systemic lupus...
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