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Article

A novel founder CHEK2 mutation is associated with increased prostate cancer risk.

Cancer research - 15 Apr 2004

Cybulski Cezary, Huzarski Tomasz, Górski Bohdan, Masojć Bartłomiej, Mierzejewski Marek, Debniak Tadeusz, Gliniewicz Bartłomiej, Matyjasik Joanna, Złowocka Elzbieta, Kurzawski Grzegorz, Sikorski Andrzej, Posmyk Michał, Szwiec Marek, Czajka Ryszard, Narod Steven A, Lubiński Jan

Abstract excerpt

Variants in the CHEK2 have been found to be associated with prostate cancer risk in the United States and Finland. We sequenced CHEK2 gene in 140 Polish patients with prostate cancer and then genotyped the three detected variants in a larger series of prostate cancer cases and controls. CHEK2 tru...

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Source

Identifiers

PMID: 15087378
DOI: 10.1158/0008-5472.can-04-0341

Genes

CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15087378-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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