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Article

<i>CHEK2</i><b><sup>∗</sup></b>1100delC Mutation and Risk of Prostate Cancer

1 Jan 2014

Abstract excerpt

Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. CHEK2 plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current knowledge of the role of a genetic variant, 1100delC, of CHEK2 on prostate cancer risk and discuss the implication for...

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PMID: 25431674
DOI: 10.1155/2014/294575

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<i>CHEK2</i><b><sup>∗</sup></b>1100delC Mutation and Risk of Prostate CancerPMID 25431674Read ↗

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